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162 results found


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Verastem Oncology, VS-7375-101, Ph 1/2, Open, KRAS G12D-Mutant solid tumors, VS-7375

Primary Objective: Part A: VS-7375 Single Agent Dose Escalation To characterize the safety, tolerability, and AE profile of escalating doses of VS-7375 as 2L+ monotherapy administered on a daily oral schedule in participants with any KRAS ...


Unknown Sites

Exelixis, Inc., XL092-311, Ph 2/3, randomized, Zanzalinitinib vs Everolimus, Neuroendocrine tumors

Primary Objective: To evaluate progression-free survival (PFS) by blinded independent central review (BICR) of zanzalintinib versus everolimus Secondary Objectives: To evaluate objective response rate (ORR) by BICR of zanzalintinib versus everolimus To evaluate overall survival (OS) of ...