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158 results found


Breast cancer

Deescalation Of Breast Radiation for Treatment of Stage I Breast Cancer

This study focuses on women with low-risk breast cancer who have had lumpectomy (surgery to remove a breast lump). The purpose of the study is to compare the usual treatment of breast radiation and hormonal ...


Brain and Nervous System

Primary CNS Lymphoma: Phase I Trial of Methotrexate, Rituximab, Lenalidomide, and Nivolumab

The purpose of this study is to determine whether the drugs rituximab, methotrexate, lenalidomide, and nivolumab can be safely combined for treatment of primary CNS lymphoma. Researchers also want to learn which dose is the ...


Prostate

Prostate Oligometastatic Radiotherapy With or Without Androgen Deprivation Therapy in Oligometastatic Prostate Cancer

This study focuses on individuals with prostate cancer. The purpose of the study is to evaluate whether a drug called relugolix plus the usual radiation therapy delays the spread of cancer compared to the usual ...


Lung

Bronchial Neuroendocrine Tumors: Lutetium Lu 177 Dotatate Versus Everolimus

This study focuses on individuals who have advanced bronchial neuroendocrine cancer and whose cancer has an increase in the expression of a receptor called the somatostatin receptor (SSTR). The purpose of the study is to ...


Lung Cancer, Non-small cell

Osimertinib and Carotuximab in Advanced, EGFR-Mutated Non-Small Cell Lung Cancer

The purpose of this study is to examine the safety and effectiveness of an experimental combination therapy of osimertinib (standard drug) with carotuximab (investigational study drug) in patients who are diagnosed with EGFR-mutated, non-small cell ...