Find Clinical Trials | Cedars-Sinai

142 results found

Lung

SWOG, S1900E, PH II, Open label, prev tx st4 / recurr KRAS G12C NSCLC, AMG 510

Primary To evaluate the response rate (confirmed, complete or partial) of AMG 510 in participants with KRASG12C mutated Stage IV or recurrent non-squamous non-small cell lung cancer (NSCLC). The response rates will be evaluated separately ...

Other Endocrine System, Pancreas

Merck, MK-6482-015, Ph 2, Open-label, PPGL & pNET, MK6482 Monotherapy

The purpose of this study is to evaluate the investigational use of a drug called belzutifan (MK-6482) in people with certain types of pheochromocytoma/ paraganglioma (PPGL) and pancreatic neuroendocrine tumors (pNET). The study will examine ...

Melanoma

ALKS 4230 as Monotherapy in Advanced Melanoma

The purpose of this study is to evaluate the effectiveness, safety, and tolerability of an experimental drug called nemvaleukin (modified interleukin-2, improves immune function towards melanoma) in people with melanoma. The study focuses on individuals ...

Brain and Nervous System

Identification of Pre-Malignant Lesions In Pediatric Patients With Neurofibromatosis Type 1

The purpose of this study is to evaluate the use of a magnetic resonance imaging (MRI) technique called whole-body MRI, combined with a computer program, in children and adolescents (5-18 years old) with neurofibromatosis type ...

Brain and Nervous System

BPM31510 With Vitamin K1 in Newly Diagnosed Glioblastoma

This study focuses on individuals who have recently been diagnosed with glioblastoma (GB), a type of brain cancer. The purpose of the study is to evaluate the safety and effectiveness of BPM31510 (an experimental drug) ...