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165 results found


Breast

BNT327 in Combination With Chemotherapy in Locally Recurrent, Inoperable or Metastatic TNBC

This study focuses on people who have triple-negative breast cancer (TNBC) that has metastasized to other organs and does not qualify for immunotherapy pembrolizumab treatment. The purpose of the study is to compare the effects ...


Solid Tumors

PEEL-224 as a Single Agent and in Combination With Vincristine and Temozolomide

This study focuses on children who have a solid tumor that has come back (relapsed) or has not responded to standard treatments (refractory). The purpose of the study is to determine whether a drug called ...


Leukemia, other, Lymphoid Leukemia

Zanubrutinib Plus Sonrotoclax-Based Therapy Compared to Continuous Zanubrutinib in Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma

This study focuses on people who have chronic lymphocytic leukemia or small lymphocytic lymphoma (CLL/SLL) that has never been treated before and whose disease has progressed to the point that therapy has been recommended. The ...


Kidney

Stereotactic Ablative Radiation Therapy for Metastatic Unresected Renal Cell Carcinoma Receiving Immunotherapy

This study focuses on people who have renal cell cancer that has spread beyond the kidney and for whom surgery is not currently recommended (or who have chosen not to have surgery). The study aims ...


Colon, Lung, Pancreas, Rectum

Kestrel Therapeutics, Inc., KST-6051, Ph I, Solid Tumors With a KRAS Mutation, KST-6051

Primary Objective: - To characterize the safety and tolerability of KST-6051 and to estimate the RDE(s) in participants with advanced or metastatic solid tumors with a KRAS mutation Secondary Objectives: - To evaluate the PK of KST-6051 after administration ...