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ELUXEO Vision Endoscopic Assessment of Tissue Oxygen Saturation

The purpose of this study is to examine gastrointestinal organs and tissues with an endoscopic device called ELUXEO Vision, which measures real-time oxygen levels in the tissue and is approved by the U.S. Food and ...


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Simvastatin Treatment to Improve Patient-Reported Outcomes in Chronic Pancreatitis

The purpose of this pilot study is to evaluate a drug called simvastatin for potential treatment of adults with recurrent acute pancreatitis or chronic pancreatitis. Participants will receive simvastatin or placebo (inactive substance); they will ...


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VS-01 in Acute-On-Chronic Liver Failure

The purpose of this study is to determine whether an investigational drug called VS-01 will help in the treatment of acute-on-chronic liver failure (ACLF) grades 1 and 2 with fluid in the abdomen (ascites). ACLF ...


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Dual Targeted Therapy in Moderate to Severe Crohn's Disease

The purpose of this study is to determine whether combining approved treatments (dual therapy) for Crohn’s disease is safe and improves patient outcomes. The treatment combinations referred to as “dual targeted therapy” are vedolizumab given ...


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Vedolizumab Dual Targeted Therapy with Tofacitinib in Ulcerative Colitis

The purpose of this study is to determine whether combining medications for ulcerative colitis (vedolizumab with tofacitinib) is safe and improves symptoms of the disease. This treatment combination is referred to as “dual targeted therapy” ...