38 results found
ATTR CM: Efficacy and Safety of NNC6019-0001 in Transthyretin Amyloid Cardiomyopathy (ATTR CM)
The purpose of this study is to determine whether an investigational drug called NNC6019-0001 can be used to treat people with transthyretin (TTR) amyloid cardiomyopathy, a heart disease due to TTR amyloidosis. Participants will undergo ...
ATTR CM: Expanded access protocol to provide patisiran in patients with ATTR amyloidosis with cardiomyopathy (APOLLO EAP)
The objective of the study is to assess the long-term safety of patisiran in patients with ATTR amyloidosis with cardiomyopathy as assessed by a review of adverse events (AEs).
Edwards_#2021-05_ALLIANCE Sapien X4
The study will use the study device (Sapien X4) in patients with severe Aortic Stenosis; it study the device's safety and effectiveness
Pulmonary Hypertension: Sotatercept versus Placebo (CADENCE)
This study focuses on individuals who have been diagnosed with a form of pulmonary hypertension (PH) associated with left heart disease, known as heart failure with preserved ejection fraction (HFpEF). PH is a disease affecting ...
Coronary Obstruction: Safety and Effectiveness of the ShortCut Device
The purpose of this study is to determine the safety and effectiveness of an investigational device called the ShortCut in individuals with a risk for coronary obstruction following a repeated bioprosthetic valve implantation. Coronary obstruction ...