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40 results found

✔ Specialty: Heart


Efficacy and Safety of CK3773274 in Symptomatic Hypertrophic Cardiomyopathy and Left Ventricular Outflow Tract Obstruction

This study focuses on individuals who have obstructive hypertrophic cardiomyopathy (oHCM, a condition in which the heart muscle is abnormally thick) and who also have left ventricular outflow tract (LVOT) obstruction, a condition that interferes ...


Efficacy and Safety of NNC6019-0001 in ATTR CM

The purpose of this study is to determine whether an investigational drug called NNC6019-0001 can be used to treat people with transthyretin (TTR) amyloid cardiomyopathy, a heart disease due to TTR amyloidosis. Participants will undergo ...


Alnylam Pharmaceuticals_ALN-TTR02-014_APOLLO EAP

The objective of the study is to assess the long-term safety of patisiran in patients with ATTR amyloidosis with cardiomyopathy as assessed by a review of adverse events (AEs).


Edwards_#2021-05_ALLIANCE Sapien X4

The study will use the study device (Sapien X4) in patients with severe Aortic Stenosis; it study the device's safety and effectiveness


Pulmonary Hypertension: Sotatercept versus Placebo

This study focuses on individuals who have been diagnosed with a form of pulmonary hypertension (PH) associated with left heart disease, known as heart failure with preserved ejection fraction (HFpEF). PH is a disease affecting ...