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Sotagliflozin in Symptomatic Obstructive And Non-Obstructive Hypertrophic Cardiomyopathy

The purpose of this study is to determine whether an experimental drug called sotagliflozin is effective in treating symptoms related to hypertrophic cardiomyopathy (HCM). HCM is a common heart condition that causes the heart muscle ...


Other

Laminar Left Atrial Appendage Elimination Pivotal IDE Study

The purpose of this study is to compare the safety and effectiveness of an experimental device called the Laminar Left Atrial Appendage Closure System with a commercially available left atrial appendage closure device that is ...


Other

Veno-Arterial ECMO Versus Off-Pump Bilateral Orthotopic Lung Transplantation

The purpose of this study is to compare the technique of performing bilateral lung transplantation off-pump versus venoarterial ECMO; researchers aim to determine which technique has lower rates of lung dysfunction. Both techniques are accepted ...


Hypertension

Therapeutic Intravascular Ultrasound (TIVUS) Renal Denervation System for the Adjunctive Treatment of Hypertension

The purpose of this study is to evaluate the safety and effectiveness of an experimental device called the TIVUS System to treat people who have hypertension (high blood pressure) that is not controlled despite treatment ...


Other

Siegel Transcatheter Aortic Valve Replacement System EFS Study

The purpose of this study is to determine whether an experimental device called the Siegel Transcatheter Aortic Valve Replacement (TAVR) System is safe and effective in treating adults who have aortic stenosis, a condition in ...