Find Clinical Trials | Cedars-Sinai

76 results found

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Ninerafaxstat in Patients With Symptomatic Non-Obstructive Hypertrophic Cardiomyopathy (FORTITUDE-HCM)

The purpose of this study is to evaluate the effects and safety of an experimental drug called ninerafaxstat in people who are experiencing symptoms from non-obstructive hypertrophic cardiomyopathy (nHCM, also called “symptomatic nHCM”). In nHCM, ...

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Danicamtiv in Symptomatic Genetic and Familial Dilated Cardiomyopathy

The purpose of this study is to evaluate whether an experimental drug called danicamtiv improves heart function in adults with dilated cardiomyopathy compared to current standard treatment. DCM is a condition in which the heart ...

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Investigation of a Novel, Magnetically Levitated VAD for Refractory Left Ventricular Heart Failure (INNOVATE Trial)

The purpose of this study is to evaluate the safety and effectiveness of an experimental device called the BrioVAD System compared to the commercially available HeartMate 3 LVAS. Both the BrioVAD System and HeartMate 3 ...

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BELIEVERS

The novelty of the BELIEVERS trial lies in being the first adequately powered, randomized study to compare TAVR and SAVR with a bioprosthesis in BAV, incorporating imaging-guided stratification to optimize outcomes, incorporating robust patient-engagement approach ...

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Coronary Intravascular Lithotripsy (IVL) Study

The purpose of this study is to evaluate the safety and effectiveness of an experimental device called the Abbott Coronary Intravascular Lithotripsy (IVL) System to widen sections of blood vessels in the heart that are ...