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Anticoagulation for Stroke Prevention in Atrial Fibrillation After Noncardiac Surgery

The purpose of this study is to determine whether long-term treatment with an approved blood thinner reduces the risk of stroke in patients who develop short-term atrial fibrillation after non-heart surgery, versus taking no blood ...


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Cardiac Radioablation Versus Repeat Catheter Ablation in Ventricular Tachycardia

The purpose of this study is to evaluate whether an experimental medical device is safe and effective in performing a treatment called cardiac radioablation in patients who have had a previous catheter ablation procedure for ...


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Combined Cardiac Contractility Modulation and Implantable Cardioverter Defibrillator Device for Heart Failure

The purpose of this study is to determine whether an investigational device called the OPTIMIZER Integra CCM-D System can effectively defibrillate (send a controlled shock to restore normal rhythm) and treat episodes of ventricular tachycardia ...


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Tafamidis in Patients With Transthyretin-Mediated Amyloidosis Post Orthotopic Heart Transplantation

The purpose of this study is to determine whether tafamidis, an oral medication used to delay disease progression in adults with certain forms of transthyretin amyloidosis (ATTR), is effective in treating patients with heart transplants ...


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MagicTouch Sirolimus-Coated Balloon in Coronary Artery Lesions of In-Stent Restenosis

The purpose of this study is to evaluate the safety and effectiveness of an experimental drug-coated balloon system called the MagicTouch sirolimus-coated balloon for the treatment of coronary in-stent restenosis (recurrence of narrowing of a ...