Find Clinical Trials | Cedars-Sinai

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Combined Cardiac Contractility Modulation and Implantable Cardioverter Defibrillator Device for Heart Failure

The purpose of this study is to determine whether an investigational device called the OPTIMIZER Integra CCM-D System can effectively defibrillate (send a controlled shock to restore normal rhythm) and treat episodes of ventricular tachycardia ...

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Tafamidis in Patients With Transthyretin-Mediated Amyloidosis Post Orthotopic Heart Transplantation

The purpose of this study is to determine whether tafamidis, an oral medication used to delay disease progression in adults with certain forms of transthyretin amyloidosis (ATTR), is effective in treating patients with heart transplants ...

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MagicTouch Sirolimus-Coated Balloon in Coronary Artery Lesions of In-Stent Restenosis

The purpose of this study is to evaluate the safety and effectiveness of an experimental drug-coated balloon system called the MagicTouch sirolimus-coated balloon for the treatment of coronary in-stent restenosis (recurrence of narrowing of a ...

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4CMedicalTechnologies_5472_AltaValve Pivotal

The purpose of this clinical trial is to evaluate the safety and effectiveness of the AltaValve System in treatment of moderate-to-severe and severe mitral regurgitation in target patient population.

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MEMENTO (CV0271088)

Primary: To evaluate the efficacy of mavacamten on the composite of LAVI and LVMI at Week 48 CMR assessment in participants with oHCM with NYHA class II or III. Secondary: To explore the effect of ...