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42 results found

✔ Specialty: Heart

Pulmonary hypertension

Pulmonary Hypertension: Sotatercept versus Placebo (CADENCE)

This study focuses on individuals who have been diagnosed with a form of pulmonary hypertension (PH) associated with left heart disease, known as heart failure with preserved ejection fraction (HFpEF). PH is a disease affecting ...


Coronary Obstruction: Safety and Effectiveness of the ShortCut Device

The purpose of this study is to determine the safety and effectiveness of an investigational device called the ShortCut in individuals with a risk for coronary obstruction following a repeated bioprosthetic valve implantation. Coronary obstruction ...


Medtronic Harmony TPV Post-Approval Study

The purpose of this study is to evaluate the functionality of transcatheter implantation (a minimally invasive procedure) of the Medtronic Harmony Transcatheter Pulmonary Valve (TPV). Significant pulmonary regurgitation (abnormal reversal of blood flow in the ...


FARAPULSE Pulsed Field Ablation System in Persistent Atrial Fibrillation

The purpose of this study to is to evaluate the safety and effectiveness of the FARAPULSE Pulsed Field Ablation System, which uses pulsed electric energy for the treatment of symptomatic persistent atrial fibrillation (irregular heart ...


Aficamten Compared to Metoprolol in Symptomatic Obstructive Hypertophic Cardiomyopathy

The purpose of this study is to compare the effectiveness and potential side effects of an investigational drug called aficamten with the beta-blocker, metoprolol, in people with obstructive hypertrophic cardiomyopathy (oHCM). Obstructive HCM is a ...