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Cardiac Radioablation Versus Repeat Catheter Ablation in Ventricular Tachycardia

The purpose of this study is to evaluate whether an experimental medical device is safe and effective in performing a treatment called cardiac radioablation in patients who have had a previous catheter ablation procedure for ...


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Combined Cardiac Contractility Modulation and Implantable Cardioverter Defibrillator Device for Heart Failure

The purpose of this study is to determine whether an investigational device called the OPTIMIZER Integra CCM-D System can effectively defibrillate (send a controlled shock to restore normal rhythm) and treat episodes of ventricular tachycardia ...


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Tafamidis in Patients With Transthyretin-Mediated Amyloidosis Post Orthotopic Heart Transplantation

The purpose of this study is to determine whether tafamidis, an oral medication used to delay disease progression in adults with certain forms of transthyretin amyloidosis (ATTR), is effective in treating patients with heart transplants ...


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MagicTouch Sirolimus-Coated Balloon in Coronary Artery Lesions of In-Stent Restenosis

The purpose of this study is to evaluate the safety and effectiveness of an experimental drug-coated balloon system called the MagicTouch sirolimus-coated balloon for the treatment of coronary in-stent restenosis (recurrence of narrowing of a ...


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Pulmonary Embolism - Thrombus Removal With Catheter-Directed Therapy

The goal of this study is to identify the best way to treat pulmonary embolism (blood clots in the lungs), specifically when there is a large amount of clot, but the patient’s blood pressure is ...