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HIS-Bundle Corrective Pacing in Heart Failure

The purpose of this study is to assess the effects of pacing-cardiac resynchronization therapy to a specific area of the heart called the His bundle (HIS-CRT), compared to biventricular pacemaker cardiac resynchronization therapy (BIV-CRT) on ...


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Cerebral Protection in Transcatheter Aortic Valve Replacement

The purpose of this study is to evaluate the safety and feasibility of an experimental filter system called the ProtEmbo Cerebral Protection System (ProtEmbo Device) in patients who are undergoing TAVR and have a risk ...


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PROGRESS Trial Continued Access Clinical Investigation Plan

The purpose of this study is to learn whether the SAPIEN 3 and SAPIEN 3 Ultra, and SAPIEN Ultra RESILIA Transcatheter Heart Valve are beneficial for patients with moderate, calcific aortic stenosis. Study procedures include ...


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WeillCornellMedicalCollege_STICH3C

The overall objective is to compare the clinical efficacy and safety of contemporary PCI and CABG to treat patients with multivessel/LM CAD and iLVSD. Primary objective: To determine whether CABG compared to PCI is associated with ...


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GORE Ascending Stent Graft in the Treatment of Lesions of the Ascending Aorta (ARISE-II)

The purpose of this study is to evaluate the safety and effectiveness of a device called the GORE Ascending Stent Graft (ASG device) to treat aortic disease. The aorta is the main artery that carries ...