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Vutrisiran in Patients With Transthyretin Amyloidosis with Cardiomyopathy

The purpose of this study is to evaluate the safety of a drug called vutrisiran (amvuttra) and determine the effects it has on people with transthyretin amyloidosis (ATTR) with cardiomyopathy (either hereditary or wild type). ...


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SELUTION SLR Drug Eluting Balloon in De Novo Coronary Lesions in Small Vessels

The purpose of this study is to determine whether an experimental device called the SELUTION SLR drug eluting balloon is safe and whether it works as effectively as other currently available treatments for patients with ...


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Follow-up Study of the Serranator PTA Serration Balloon Catheter

This study focuses on people who have peripheral artery disease or a dysfunctional arteriovenous fistula and will be treated as part of routine standard care with a device called the Serranator PTA Serration Balloon Catheter ...


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Optimal Adult Heart Transplant Immunosuppresion With MicroRNA Levels

The purpose of this study is to identify blood biomarkers that could be used to predict infection and rejection after heart transplant. A biomarker is a biological molecule found in blood or other body fluids ...


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Sirolimus-Coated Balloon Vs. Standard Balloon Angioplasty in Below-The-Knee Arterial Disease

The purpose of this study is to determine whether an experimental balloon device is effective in treating peripheral arterial disease (insufficient blood flow in the legs). The device, called Magic Touch PTA, is covered with ...