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46 results found

Heart failure

Heart Failure and Reduced Ejection Fraction: A Pilot Study to Increase Utilization of Guideline Directed Medical Therapy in Patients with Heart Failure and Reduced Ejection Fraction Using a Digital Therapeutics Platform

Primary -Percentage of time that the treating clinician agrees with the DE GDMT medication recommendations. For this endpoint, all patients will be considered regardless of enrollment time and will begin after RPM has been initiated. Key Secondary -The ...


Tricuspid Regurgitation: Study of the TTVR Transfemoral System

This study focuses on individuals who have tricuspid regurgitation (TR), a condition in which the heart’s tricuspid valve does not close tightly, causing the blood to leak backwards. The study will evaluate the use of ...


The PROGRESS Trial: Management of Moderate Aortic Stenosis by Clinical Surveillance or Transcatheter Aortic Valve Replacement

The purpose of this study is to learn whether the SAPIEN 3 and SAPIEN 3 Ultra Transcatheter Heart Valve are beneficial for individuals with moderate, calcific aortic stenosis. Patients with moderate aortic stenosis may or ...

Heart failure

Heart Failure: In-Hospital Initiation of Dapagliflozin in Acute Heart Failure (DAPA ACT HF-TIMI 68)

The purpose of this study is to evaluate whether a drug called dapagliflozin is safe and effective when added to conventional heart failure therapy in patients who have been admitted to the hospital for acute ...


Anticoagulation for New-Onset Post-Operative Atrial Fibrillation after CABG (PACeS)

This study focuses on individuals who have undergone recent coronary artery bypass graft surgery (CABG), also known as bypass surgery. The purpose of the study is to compare 2 commonly used treatment strategies for the ...