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Mavacamten in Heart Failure With HFpEF and Chronic Elevation of Cardiac Biomarkers

This study focuses on individuals who have a condition called HFpEF (heart failure with preserved ejection fraction). HFpEF occurs when the lower left chamber (left ventricle) is not able to fill properly with blood during ...


Mitral Valve Regurgitation

SAPIEN M3 System TransCatheter Mitral Valve ReplaCement via Transseptal Access  

The purpose of this study is to examine the safety and effectiveness of the investigational SAPIEN M3 System, a mitral valave replacement system, in patients with blood backflow (mitral regurgitation) across the mitral valve. The ...


Valvular Heart Disease

REPAIR MR

The purpose of this study is to evaluate the safety and effectiveness of an investigational medical device called the MitraClip Mitral Valve Repair System (MitraClip System) in patients with severe primary mitral regurgitation who are ...


Heart failure

Heart Failure and Reduced Ejection Fraction: A Pilot Study to Increase Utilization of Guideline Directed Medical Therapy in Patients with Heart Failure and Reduced Ejection Fraction Using a Digital Therapeutics Platform

Primary -Percentage of time that the treating clinician agrees with the DE GDMT medication recommendations. For this endpoint, all patients will be considered regardless of enrollment time and will begin after RPM has been initiated. Key Secondary -The ...


Other

Tricuspid Regurgitation: Study of the TTVR Transfemoral System

This study focuses on individuals who have tricuspid regurgitation (TR), a condition in which the heart’s tricuspid valve does not close tightly, causing the blood to leak backwards. The study will evaluate the use of ...