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40 results found

✔ Specialty: Heart

Valvular Heart Disease


The purpose of this study is to evaluate the safety and effectiveness of an investigational medical device called the MitraClip Mitral Valve Repair System (MitraClip System) in patients with severe primary mitral regurgitation who are ...



Primary -Percentage of time that the treating clinician agrees with the DE GDMT medication recommendations. For this endpoint, all patients will be considered regardless of enrollment time and will begin after RPM has been initiated. Key Secondary -The ...


Tricuspid Regurgitation: Study of the TTVR Transfemoral System

This study focuses on individuals who have tricuspid regurgitation (TR), a condition in which the heart’s tricuspid valve does not close tightly, causing the blood to leak backwards. The study will evaluate the use of ...


The PROGRESS Trial: Management of Moderate Aortic Stenosis by Clinical Surveillance or Transcatheter Aortic Valve Replacement

The purpose of this study is to learn whether the SAPIEN 3 and SAPIEN 3 Ultra Transcatheter Heart Valve are beneficial for individuals with moderate, calcific aortic stenosis. Patients with moderate aortic stenosis may or ...


In-Hospital Initiation of Dapagliflozin in Acute Heart Failure

The purpose of this study is to evaluate whether a drug called dapagliflozin is safe and effective when added to conventional heart failure therapy in patients who have been admitted to the hospital for acute ...