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48 results found


The PROGRESS Trial: Management of Moderate Aortic Stenosis by Clinical Surveillance or Transcatheter Aortic Valve Replacement

The purpose of this study is to learn whether the SAPIEN 3 and SAPIEN 3 Ultra Transcatheter Heart Valve are beneficial for individuals with moderate, calcific aortic stenosis. Patients with moderate aortic stenosis may or ...

Heart failure

Heart Failure: In-Hospital Initiation of Dapagliflozin in Acute Heart Failure (DAPA ACT HF-TIMI 68)

The purpose of this study is to evaluate whether a drug called dapagliflozin is safe and effective when added to conventional heart failure therapy in patients who have been admitted to the hospital for acute ...



To assess the safety and effectiveness of the AgentTM Paclitaxel Coated PTCA Balloon Catheter compared to balloon angioplasty (POBA) in patients with in-stent restenosis (ISR) of a previously treated lesion of up to 26 mm ...


Anticoagulation for New-Onset Post-Operative Atrial Fibrillation after CABG (PACeS)

This study focuses on individuals who have undergone recent coronary artery bypass graft surgery (CABG), also known as bypass surgery. The purpose of the study is to compare 2 commonly used treatment strategies for the ...


Pulmonary Embolism: Safety and Outcomes of Indigo Aspiration System

This study focuses on individuals who have had a pulmonary embolism (PE) and whose doctor has determined that the clot should be removed to prevent damage to the heart and lungs. A PE is a ...