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Balloon-Expandable Bioprosthetic SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic Valves

This study focuses on people who have an existing bioprosthetic aortic valve that is failing and needs to be replaced and who fall in the high or greater risk category for open heart surgery. The ...


Other

PROGRESS Trial Continued Access Clinical Investigation Plan

The purpose of this study is to learn whether the SAPIEN 3 and SAPIEN 3 Ultra, and SAPIEN Ultra RESILIA Transcatheter Heart Valve are beneficial for patients with moderate, calcific aortic stenosis. Study procedures include ...


Cardiomyopathy - ischemic

Canadian CABG or PCI in Patients with Ischemic Cardiomyopathy (STICH3C)

This study focuses on people who have multivessel coronary artery disease (blockages in the blood vessels supplying the heart muscle) and ischemic left ventricular dysfunction (weak heart from reduced coronary blood flow secondary to the ...


Other

GORE Ascending Stent Graft in the Treatment of Lesions of the Ascending Aorta (ARISE-II)

The purpose of this study is to evaluate the safety and effectiveness of a device called the GORE Ascending Stent Graft (ASG device) to treat aortic disease. The aorta is the main artery that carries ...


Other

Hearts Transplanted After Non-Ischemic Heart Preservation from Extended Donors

The purpose of this study is to evaluate whether non-ischemic heart preservation (NIHP) of extended criteria donor hearts using the XVIVO Heart Preservation System (XHPS) is a safe and effective way to preserve and transport ...