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49 results found


Pulmonary hypertension

Treprostinil Palmitil Inhalation Powder in Pulmonary Arterial Hypertension

The purpose of this study is to evaluate an experimental drug called treprostinil palmitil inhalation powder (TPIP) for the treatment of pulmonary arterial hypertension (PAH). The study aims to determine the safety, tolerability, and effectiveness ...


Atrial fibrillation

Paroxysmal Atrial Fibrillation: Synaptic Compliant Cryoablation Balloon and System

The purpose of this study is to determine whether an investigational medical device called the Synaptic Cryoablation System is safe and effective for treating paroxysmal atrial fibrillation. Atrial fibrillation is an abnormal heart rhythm in ...


Other

Thoraflex Hybrid and Relay Extension Post-Approval Study

The purpose of this study is to gather further information on the standard-of-care use of a device called the Thoraflex Hybrid alone and in combination with the RelayPro NBS Stent-Graft to treat aortic disease. The ...


Other

Lorundrostat in Uncontrolled Hypertension

The purpose of this study is to assess the blood pressure lowering effect of an experimental drug called lorundrostat (MLS 101) in combination with medications (that are approved by the U.S. Food and Drug Administration-FDA) ...


Other

Eplontersen in Transthyretin-Mediated Amyloid Cardiomyopathy

The purpose of this study is to evaluate the safety and effectiveness of an experimental drug called eplontersen in people with transthyretin-mediated amyloid cardiomyopathy (ATTR-CM). ATTRCM is a disease caused by change in a protein ...