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52 results found


Hypertension

ReCor Medical Paradise System in Clinical Hypertension

The purpose of this study is to continue to collect data on the safety and effectiveness of a medical device called the Paradise Ultrasound Renal Denervation System (also called the Paradise System) in patients who ...


Cardiomyopathy - non-obstructive hypertrophic (nHCM)

Mavacamten in Symptomatic Non-Obstructive Hypertrophic Cardiomyopathy

The purpose of this study is to determine whether treatment with a drug called mavacamten reduces shortness of breath and fatigue and increases exercise capacity in patients with non-obstructive hypertrophic cardiomyopathy (nHCM). Study procedures include ...


Mitral Valve Regurgitation

Mitral Valve Regurgitation: Transseptal Mitral Valve Replacement System - Early Feasibility Study

The purpose of this study is to determine the safety and effectiveness of an investigational device called the Innovalve TMVR system for the treatment of a leaking mitral valve (mitral valve regurgitation). Mitral valve regurgitation ...


Pulmonary hypertension

Treprostinil Palmitil Inhalation Powder in Pulmonary Arterial Hypertension

The purpose of this study is to evaluate an experimental drug called treprostinil palmitil inhalation powder (TPIP) for the treatment of pulmonary arterial hypertension (PAH). The study aims to determine the safety, tolerability, and effectiveness ...


Atrial fibrillation

Paroxysmal Atrial Fibrillation: Synaptic Compliant Cryoablation Balloon and System

The purpose of this study is to determine whether an investigational medical device called the Synaptic Cryoablation System is safe and effective for treating paroxysmal atrial fibrillation. Atrial fibrillation is an abnormal heart rhythm in ...