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12 results found


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Levosimendan in PH-HFpEF

This study focuses on people who have pulmonary hypertension with heart failure with preserved ejection fraction (PH-HFpEF), also known as diastolic heart failure or diastolic dysfunction. This is a type of heart failure in which ...


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Pirfenidone Solution for Inhalation (AP01) in Progressive Pulmonary Fibrosis

The purpose of this study is to evaluate the safety and effectiveness of multiple doses of an experimental drug called AP01 compared with placebo (inactive substance) in people who have progressive pulmonary fibrosis (PPF). The ...


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Targeting Inflammation and Alloimmunity in Lung Transplant Recipients With Tocilizumab

This study focuses on people who are about to have a lung transplant. The purpose of the study is to determine whether a drug called tocilizumab will, when given with standard anti-rejection medicines, lead to ...


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Adjunctive Recombinant Human Plasma Gelsolin With Standard of Care for Moderate-to-Severe ARDS

The purpose of this study is to evaluate an experimental medication called gelsolin (recombinant human plasma gelsolin) in people who have moderate to severe acute respiratory distress syndrome (ARDS) due to pneumonia or other infections. ...


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Nebulized PC945 and Systemic Antifungal Therapy in Refractory Invasive Pulmonary Aspergillosis

This study focuses on people who have been diagnosed with invasive pulmonary aspergillosis (IPA, a lung infection caused by a common fungus found in the environment called aspergillus) and who are not responding well to ...