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Inhaled Nitric Oxide for ARDS-Related Pulmonary Hypertension

The purpose of this study is to determine whether giving inhaled nitric oxide to adults with acute respiratory distress syndrome (ARDS) who have developed pulmonary hypertension (elevated blood pressure in the blood vessels of the ...


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Evaluation of Interventions for Sleep Disturbances in PASC

The purpose of this study is to determine whether certain interventions can help treat sleep disturbances that started or worsened following a COVID infection and have lasted for at least 12 weeks. Sleep disturbances include ...


Other

Levosimendan in PH-HFpEF

This study focuses on people who have pulmonary hypertension with heart failure with preserved ejection fraction (PH-HFpEF), also known as diastolic heart failure or diastolic dysfunction. This is a type of heart failure in which ...


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Pirfenidone Solution for Inhalation (AP01) in Progressive Pulmonary Fibrosis

The purpose of this study is to evaluate the safety and effectiveness of multiple doses of an experimental drug called AP01 compared with placebo (inactive substance) in people who have progressive pulmonary fibrosis (PPF). The ...


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Adjunctive Recombinant Human Plasma Gelsolin With Standard of Care for Moderate-to-Severe ARDS

The purpose of this study is to evaluate an experimental medication called gelsolin (recombinant human plasma gelsolin) in people who have moderate to severe acute respiratory distress syndrome (ARDS) due to pneumonia or other infections. ...