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PLS Natural History Study (PNHS)

Primary lateral sclerosis (PLS) has been largely neglected in terms of research, primarily because it is so rare. The purpose of this study is to change the current research status ...


Other

A Phase 3, multicenter, randomized, double-blind, placebo-controlled study to assess the efficacy, safety...

This study focuses on individuals who have been diagnosed with probable Alzheimer’s disease (AD) and have agitation. Agitated behaviors such as irritability and restlessness, physical/verbal ...


Other

A double-blind, randomized, placebo-controlled study to evaluate the efficacy and safety of intravenous ganaxolone...

Status epilepticus is a serious condition that requires immediate treatment to stop the seizures and prevent permanent brain damage. The ...


Other

A Randomized, Double-Blind, Placebo-Controlled Study to Assess Safety, Tolerability, and Pharmacokinetics Following Multiple...

To assess the safety, tolerability, and pharmacokinetics (PK) of A-1684909 following multiple doses of ABBV-CLS-7262 (A-1684909 prodrug) in subjects with amyotrophic lateral sclerosis (ALS).


Other

A Multi-Center, Controlled Study to Evaluate use of CereGate Therapy to Reduce Freezing...

The purpose of this study is to determine whether using CereGate therapy with deep brain stimulation (DBS) reduces freezing of gait in individuals diagnosed with Parkinson’s Disease (PD) who have ...