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24 results found

✔ Specialty: Neurosurgery

Primary lateral sclerosis (PLS)

PLS Natural History

Primary lateral sclerosis (PLS) has been largely neglected in terms of research, primarily because it is so rare. The purpose of this study is to change the current research status of PLS by collecting clinical ...

Alzheimer's disease

AVP-786 for the Treatment of Agitation in Dementia of the Alzheimer's Type

This study focuses on individuals who have been diagnosed with probable Alzheimer’s disease (AD) and have agitation. Agitated behaviors such as irritability and restlessness, physical/verbal aggression, pacing and wandering are major problems in Alzheimer’s patients. ...


Efficacy and Safety of Intravenous Ganaxolone in Status Epilepticus

Status epilepticus is a serious condition that requires immediate treatment to stop the seizures and prevent permanent brain damage. The purpose of this study is to determine whether an investigational drug called ganaxolone can stop ...

Amyotrophic lateral sclerosis (ALS)


To assess the safety, tolerability, and pharmacokinetics (PK) of A-1684909 following multiple doses of ABBV-CLS-7262 (A-1684909 prodrug) in subjects with amyotrophic lateral sclerosis (ALS).


CereGate Therapy to Reduce Freezing of Gait in Parkinson’s Disease

The purpose of this study is to determine whether using CereGate therapy with deep brain stimulation (DBS) reduces freezing of gait in individuals diagnosed with Parkinson’s Disease (PD) who have been implanted with a Boston ...