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5 results found


Breast cancer, Colon cancer, Lung Cancer, Melanoma, Rectal Cancer, Solid ...

GV20-0251 in Advanced and/or Refractory Solid Tumor Malignancies

The purpose of the study is to determine whether an experimental drug called GV20-0251 is safe and tolerable in patients with solid tumors that have not been successfully treated with standard therapies. GV20-0251 is a ...


Breast cancer

Deescalation Of Breast Radiation for Treatment of Stage I Breast Cancer

This study focuses on women with low-risk breast cancer who have had lumpectomy (surgery to remove a breast lump). The purpose of the study is to compare the usual treatment of breast radiation and hormonal ...


Breast cancer

T-DM1 and Placebo Compared With T-DM1 AND Tucatinib in HER2-Positive Breast Cancer

This study focuses on patients who have human epidermal growth factor receptor 2 (HER2)-positive breast cancer and who have already received treatment with chemotherapy and anti-HER2 targeted therapies followed by surgery. The study will evaluate ...


Breast cancer

Ivermectin and Balstilimab in Metastatic Triple Negative Breast Cancer

The purpose of this study is to evaluate whether concurrent use of oral ivermectin and intravenous (IV) balstilimab is safe and effective in treating patients with triple negative breast cancer. Researchers want to know the ...


Breast cancer

De-Escalation of Therapy in Early-Stage TNBC

This study focuses on patients who have been diagnosed with early-stage, triple-negative breast cancer (TNBC) and have recently completed preoperative chemotherapy in combination with the immunotherapy drug pembrolizumab, followed by breast surgery. The purpose of ...