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25 results found


Melanoma

Sarilumab Combined With Ipilimumab, Nivolumab, and Relatlimab in Advanced/Unresectable Melanoma

This study will evaluate the safety and tolerability of a drug called sarilumab in combination with ipilimumab, nivolumab, and relatlimab in advanced/unresectable melanoma (melanoma that cannot be removed by surgery). Ipilimumab, nivolumab, and relatlimab ...


Melanoma

IMC-F106C Plus Nivolumab Versus Nivolumab Regimens in Advanced Melanoma

This study focuses on adults with advanced melanoma (a type of skin cancer) that has spread or cannot be surgically removed. The purpose of the study is to determine whether an experimental drug called IMC-F106C, ...


Melanoma

GIM-531 as a Single Agent and in Combination With Anti-PD-1 in Advanced Solid Tumors

This study focuses on individuals who have been diagnosed with advanced stage cancer. The purpose of the study is to determine whether an experimental drug called GIM-531 is safe and can help the immune system ...


Melanoma

OBX-115 in Unresectable or Metastatic Melanoma

The goal of this study is to determine the recommended dose of an experimental cell therapy called OBX-115 with another medication called acetazolamide (approved by the U.S. Food and Drug Administration as a mild diuretic) ...


Melanoma

Vusolimogene Oderparepvec in Combination With Nivolumab in Advanced Melanoma

The purpose of this study is to evaluate an experimental drug called vusolimogene oderparepvec (VO) in combination with another drug, nivolumab, in people who have advanced melanoma. Researchers will compare the effects of nivolumab with ...