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25 results found


Breast, Esophagus, Larynx, Lip, Oral Cavity and Pharynx, Lung, Melanoma ...

INCA33890 in Advanced or Metastatic Solid Tumors

The purpose of this study is to determine the safest and most effective dose of an experimental drug called INCA33890 in people with selected advanced or metastatic solid tumors. INCA33890 is an immune therapy (drug ...


Bones and Joints, Breast, Cervix, Colon, Kidney, Liver, Lung, Melanoma ...

PARG Inhibitor IDE161 in Advanced Solid Tumors

This study focuses on individuals who have a solid tumor cancer (not a blood cancer) that has worsened and has not responded to at least one prior cancer treatment. The purpose of the study is ...


Eye and Orbit, Melanoma

IDE196 in Combination with Crizotinib in Metastatic Uveal Melanoma

The purpose of this study is to determine whether an experimental medication, IDE196 (also called darovasertib), in combination with another drug, crizotinib, is safe and effective in people who have cancer in their eye (uveal ...


Colon, Lip, Oral Cavity and Pharynx, Melanoma, Pancreas

IPN01194 as Single Agent in Advanced Solid Tumors

The purpose of this study is to evaluate an experimental drug called IPN01194 in people with selected mutations in advanced solid cancers. IPN01194 is a small molecule targeting a pathway called MAPK, which is frequently ...


Anus, Bones and Joints, Brain and Nervous System, Breast, Cervix ...

Molecular Analysis for Combination Therapy Choice (ComboMATCH)

The purpose of this study is to identify patients based on gene changes or mutations in their tumor for treatment using a combination of targeted therapy. The study focuses on patients who have had a ...