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135 results found


Brain and Nervous System

Carboplatin and Vincristine Versus Selumetinib in Low-Grade Glioma

This study focuses on individuals who have been diagnosed with a cancer called low-grade glioma (LGG). The purpose of the study is to determine whether an experimental drug called selumetinib is as effective as the ...


Cervix, Liver, Lung, Melanoma, Small Intestine, Stomach, Urinary Bladder

BA3071 in Combination With Nivolumab in Patients With Advanced Solid Tumors

The purpose of this study is to evaluate an investigational drug called BA3071 as a potential treatment in combination with another drug, nivolumab, in patients with advanced solid tumor cancers. Nivolumab is an immunotherapy approved ...


Lung Cancer, Non-small cell

Osimertinib and Carotuximab in Advanced, EGFR-Mutated Non-Small Cell Lung Cancer

The purpose of this study is to examine the safety and effectiveness of an experimental combination therapy of osimertinib (standard drug) with carotuximab (investigational study drug) in patients who are diagnosed with EGFR-mutated, non-small cell ...


Melanoma

Melanoma Margins Trial: 1cm v 2cm Wide Excision Margins for Primary Cutaneous Melanoma

This study focuses on individuals who have been diagnosed with a form of skin cancer called melanoma, which develops from melanocytes (pigment cells). During surgery for melanoma, the skin cancer and a small margin of ...


Lung Cancer

Novel MRI Sequences and Blood-Based Biomarkers for Discriminating Cancerous Nodules

The purpose of this study is to determine how many people from a lung cancer screening program will take part in a study to support magnetic resonance imaging (MRI) and blood-based biomarker research for lung ...