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135 results found


Lifestyle, Prostate cancer

Fasting-Mimicking Diet to Improve Prostate Cancer Control and Metabolic Outcomes

The purpose of this study is to evaluate how a fasting-mimicking diet versus a usual diet influences cancer treatment of metastatic castrate-sensitive prostate adenocarcinoma. The fasting-mimicking diet is a 5-day program of plant-based products that ...


Bladder cancer, Ovarian cancer, Uterine cancer

Acrivon Ther, ACR-368-201/GOG-3082,Ph1b/2,Open-label,Ovarian/endometrial/uroth,ACR-368+/-Gemcitabine

Primary Arm 1 Assess the anti-tumor activity of ACR-368 monotherapy in each cohort (ovarian, endometrial, urothelial) of OncoSignature Positive subjects. Arm 2 Assess the safety and tolerability of ACR-368 in combination with LDG Determine the RP2D of LDG Secondary Arm 1 Confirmation of ...


Lung

Non-Small Cell Lung Cancer: Lung-MAP Sub-Study

The purpose of this study is to determine whether a combination of drugs (capmatinib, osimertinib, and ramucirumab) is beneficial compared to another combination (capmatinib and osimertinib) for treating non-small cell lung cancer tumors that have ...


Ovary

Comparing the Non-Inferiority of Salpingectomy to Salpingo-Oophorectomy to Reduce the Risk of Ovarian Cancer

This study aims to determine whether 2 surgical procedures are no different for ovarian cancer risk reduction in individuals with BRCA1 mutations who have completed childbearing. (Mutations in the BRCA1 gene are associated with a ...


Breast

Da Vinci SP Surgical System in Nipple-Sparing Mastectomy

The purpose of this clinical study is to collect data about the use of a robotic device called the da Vinci Single-Port (SP) Surgical System in nipple-sparing mastectomy (NSM) procedures. NSM is a surgery for ...