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157 results found


Prostate

Epigenetic Therapy Before Prostatectomy in Men With Prostate Cancer

This study focuses on people who have prostate cancer and are planning to have a radical prostatectomy (removal of prostate and some surrounding tissue). The purpose of the study is to assess the safety, tolerability, ...


Melanoma

PF-07799544 as a Single Agent and in Combination With Other Targeted Agents in BRAF-Mutant Melanoma and Other Solid Tumors

This study focuses on people who have melanoma (skin cancer) or other cancer with a specific change in the BRAF gene (BRAF alteration) and whose cancer has grown or spread. The study will explore the ...


Non-Hodgkin Lymphoma, Other Hematopoietic

MK-2140 in Combination With R-CHP Versus R-CHOP in Diffuse Large B-Cell Lymphoma

The purpose of this study is to evaluate the safety and effectiveness of the combination of an experimental drug called zilovertamab vedotin (MK-2140) plus a series of cancer drugs (R-CHP) in treating people with diffuse ...


Lung

Lung-MAP Non-Matched Sub-Study

This study focuses on people who have advanced non-small cell lung cancer (NSCLC) and who had previous treatment using chemotherapy that contains platinum and immunotherapy. The study is part of Lung-MAP, a large research project ...


Melanoma

Cemiplimab plus Ziv-Aflibercept in Metastatic Uveal Melanoma

The purpose of this phase II study for advanced melanoma is to evaluate the safety (side effects profile) and effectiveness (tumor shrinkage) of cemiplimab and ziv-aflibercept, when given together. Cemiplimab is an anti-cancer drug called ...