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155 results found


Ovary

Olaparib With or Without Bevacizumab in BRCA 1/2 Mutated or Homologous Recombination Deficient Ovarian Cancer

This study focuses on people with ovarian cancer who have tested positive for BRCA1/2 mutation (change or defect in the BRCA gene) or homologous recombination deficiency (when the body cannot repair breaks in DNA). The ...


Leukemia, other

Venetoclax Plus Chemotherapy For Newly Diagnosed Acute Myeloid Leukemia

This study focuses on people who have a new diagnosis of acute myeloid leukemia (AML) who agreed to participate in the MyeloMATCH study and were matched to this treatment trial. The purpose of the study ...


Unknown Sites

Neoadjuvant Immunotherapy With Response-Adapted Treatment in Resectable Stage III/IV Cutaneous Squamous Cell Carcinoma

This study focuses on people who have advanced squamous cell skin cancer that can be removed with surgery. The purpose of the study is to determine whether giving an immunotherapy drug called cemiplimab before and ...


Lip, Oral Cavity and Pharynx

Using Circulating Tumor DNA to Risk Adapt Post-Operative Therapy for HPV-Associated Oropharyngeal Cancer

The purpose of this study is to determine whether using less intense radiation therapy and chemotherapy (chemoradiation) after trans-oral robotic surgery (TORS) will be as effective in treating HPV-associated oropharyngeal cancer as standard treatment while ...


Breast

Defining Lipidomic and Immune Signatures of Aromatase Inhibitor-Associated Musculoskeletal Symptoms

The purpose of this study is to examine biological molecules in the blood that may predict the onset and severity of aromatase inhibitor-associated musculoskeletal symptoms (AIMSS). AIMSS is a condition that affects some patients who ...