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152 results found


Unknown Sites

AMG 510 With or Without Panitumumab in Advanced Solid Tumors

This study focuses on individuals who have an advanced solid tumor and whose cancer has a change in the gene called KRAS G12C. The purpose of the study is to evaluate the effects of the ...


Other Female Genital, Unknown Sites

Neratinib Alone or in Combination with Palbociclib in HER2+ Cancers and Other Solid Tumors

This study focuses on individuals who have recurrent or persistent cancer and whose cancer expresses a protein called HER2 (human growth factor receptor 2). The purpose of the study is to determine whether a combination ...


Unknown Sites

Paclitaxel and Ipatasertib In PTEN/AKT-Altered Advanced Non-Breast Solid Tumors

The purpose of this study is to evaluate the effects of combining a drug called ipatasertib with the chemotherapy drug paclitaxel in people who have advanced cancer and whose cancer has a change in genes ...


Other

Phase II Study of Unresectable Hepatocellular Carcinoma and Cirrhosis

The purpose of this study is to evaluate the effects of combined immunotherapy regimens (atezolizumab with bevacizumab) in patients with inoperable liver cancer and liver disease (cirrhosis). Participants may receive atezolizumab alone (if they are ...


Corpus Uteri, Ovary

Selumetinib and Olaparib or Selumetinib Alone in Ovarian and Endometrial Cancers

This study focuses on people who have recurrent or persistent ovarian or endometrial cancer and whose cancer has a change in the gene family called RAS genes. The purpose of the study is to compare ...