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155 results found


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VEGFR2/MET Inhibitor Cabozantinib in Combination With Cytotoxic Chemotherapy for Newly Diagnosed Osteosarcoma

This study focuses on individuals who have a type of bone cancer called osteosarcoma (OST). The purpose of the study is to evaluate how well an experimental drug called cabozantinib works in combination with methotrexate, ...


Urinary Bladder

Bladder Preservation with Immunoradiotherapy in Muscle Invasive Bladder Cancer

This study focuses on people who have responded to chemotherapy or chemotherapy-like treatment for muscle invasive bladder cancer, and the cancer has either shrunk or cannot be found. The purpose of the study is to ...


Lymphoid Leukemia, Non-Hodgkin's Lymphoma

Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid in Diffuse-Large B-Cell Lymphoma and High-Grade B-Cell Lymphoma

The purpose of this study is to determine whether treatment with ViPOR (a combination of the drugs venetoclax, ibrutinib, prednisone, obinutuzumab, and lenalidomide) will lead to disappearance of all sites of cancer (i.e., complete remission) ...


Brain and Nervous System

Single Fraction Stereotactic Radiosurgery Versus Fractionated SRS For Intact Brain Metastases

This study focuses on people who are having stereotactic radiosurgery (SRS) to treat cancer that has spread to their brain. The purpose of the study is to determine whether a type of SRS radiation treatment ...


Ovary

Ubamatamab in Platinum-Resistant Ovarian Cancer

The purpose of this study is to evaluate an investigational drug called ubamatamab in patients who have advanced ovarian cancer. Researchers want to determine how safe, tolerable, and effective ubamatamab is on its own and ...