Find Clinical Trials | Cedars-Sinai

159 results found

Colon, Lung, Melanoma, Rectum

mRNA-4359 Alone and in Combination With Immune Checkpoint Blockade

This study focuses on people who have locally advanced, metastatic, or relapsed solid tumor cancer (cancer that can be measured and has worsened and become larger and/or spread to other parts of the body). The ...

Prostate

CCTG/NRG, CCTG-PR26, Ph 3, rand, prostate cancer, Docetaxel + androgen inhibitors

Primary Objective: To compare overall survival (OS) in participants with mCSPC who are receiving standard of care ADT (between 6-12 months exposure) + ARPI (>= 4-months exposure) and have suboptimal PSA response (PSA >=0.2 ng/ml at ...

Prostate

Standard Systemic Therapy Vs. Standard Systemic Therapy Plus Definitive Treatment in Metastatic Prostate Cancer

The purpose of this study is to compare the effects of adding either prostate removal surgery or radiation therapy to standard systemic therapy for the treatment of metastatic prostate cancer. Researchers aim to determine whether ...

Small Intestine, Stomach

DRX-42 Versus Sunitinib in Metastatic and/or Unresectable Gastrointestinal Stromal Tumors After Imatinib Therapy

The purpose of this study is to determine the safety and effectiveness of an experimental drug called IDRX-42 compared to a drug called sunitinib (standard-of-care treatment) in people who have been diagnosed with advanced gastrointestinal ...

Breast

Reinvigorating Response To Immunotherapy in Triple-Negative Breast Cancer With Combination Myeloid Inhibition and Radiation

The purpose of this study is to evaluate the safety and effectiveness of a drug called pembrolizumab in combination with radiation therapy and another drug, axatilimab, in the treatment of patients with metastatic or locally ...