Find Clinical Trials | Cedars-Sinai

155 results found

Kidney

Short-Term Intensified Pembrolizumab and Tivozanib for High-Risk Renal Cell Carcinoma

The purpose of this study is to evaluate whether the addition of a drug called tivozanib to another drug, pembrolizumab, is better than the usual approach (pembrolizumab alone) for treating advanced kidney cancer. Specifically, researchers ...

Prostate

Ifinatamab Deruxtecan Versus Docetaxel in Metastatic Castration-Resistant Prostate Cancer

The purpose of this study is to evaluate the safety and effectiveness of an experimental drug called ifinatamab deruxtecan (I-DXd) in treating people with metastatic castration-resistant prostate cancer (mCRPC), as compared to the standard-of-care treatment, ...

Unknown Sites

BL-M07D1 in Subjects With HER2 Expressing Advanced Malignant Solid Tumors

The purpose of this study is to evaluate the safety, tolerability, and effectiveness of an experimental drug called BL-M07D1 as a possible treatment for people who have a type of advanced, inoperable cancer that expresses ...

Breast

BriaCell Therapeutics, BC-IMT-04, Ph 3, Rand/Open label, Breast Ca, Bria-IMT + CPI vs TPC

Primary Objective: To evaluate the effect of the Bria-IMT regimen in combination with Check Point Inhibitor (CPI) on overall survival (OS). Secondary Objectives: To evaluate the effect of the Bria-IMT regimen with CPI on progression-free survival (PFS) To evaluate ...

Lung

BioNTech, BNT324-01, Ph Ib/II, Open-label, BNT324 + BNT327, Advanced Lung Cancer

Part 1 Primary: To determine the RP2D of BNT324 in combination with BNT327 by assessing the safety and tolerability in participants with advanced lung cancer. Secondary: To evaluate the efficacy of BNT324 in combination with BNT327 according to RECIST 1.1. Part ...