Find Clinical Trials | Cedars-Sinai

150 results found

Prostate

Epigenetic Therapy Before Prostatectomy in Men With Prostate Cancer

This study focuses on people who have prostate cancer and are planning to have a radical prostatectomy (removal of prostate and some surrounding tissue). The purpose of the study is to assess the safety, tolerability, ...

Breast

Pfizer, C4391024, Ph3, Open-label, randomized, Br CA, PF-07220060+Letrozole vs CDK4/6+ Letrozole

Primary Objective: To compare the efficacy of PF07220060 in combination with letrozole (Arm A) versus CDK4/6i (investigator s choice: abemaciclib, palbociclib, or ribociclib) in combination with letrozole (Arm B) with respect to progression-free survival (PFS). Secondary Objectives: To ...

Other Female Genital

Sacituzumab Govitecan Versus Treatment of Physician’s Choice in Endometrial Cancer

The purpose of this study is to learn whether an experimental drug called sacituzumab govitecan (also called SG or Trodelvy) can help patients with endometrial cancer that has spread or recurred to live longer compared ...

Other Hematopoietic

MK-2140 in Combination With R-CHP Versus R-CHOP in Diffuse Large B-Cell Lymphoma

The purpose of this study is to evaluate the safety and effectiveness of the combination of an experimental drug called zilovertamab vedotin (MK-2140) plus a series of cancer drugs (R-CHP) in treating people with diffuse ...

Lung

SWOG, S1800E, PhII/III, Randomized, Doetaxel + Ramucirumab +/- Cemiplimab, NSCLC

Primary Objective: The primary objective of the study is to compare overall survival (OS) between participants randomized to docetaxel and ramucirumab with or without cemiplimab (REGN2810) who have acquired resistance to platinum-based chemotherapy and ...