Find Clinical Trials | Cedars-Sinai

13 results found

Lymphoid Leukemia

AZD0486 in Adolescents and Adults With Relapsed or Refractory B-Cell Acute Lymphoblastic Leukemia

The purpose of this study is to learn more about an experimental drug called AZD0486 and determine whether it will be safe, tolerable, and effective in treating B-cell acute lymphoblastic leukemia (B-ALL). AZD0486 is ...

Leukemia, other

Venetoclax and HMA-based Therapies for Adults With FLT3-mutated Acute Myeloid Leukemia: A MyeloMATCH Treatment Trial

This study focuses on adults diagnosed with acute myeloid leukemia (AML) who have previously participated in another study called the myeloMATCH study. The purpose of this research is to compare the usual drug combination treatment ...

Ovary

Olaparib With or Without Bevacizumab in BRCA 1/2 Mutated or Homologous Recombination Deficient Ovarian Cancer

This study focuses on people with ovarian cancer who have tested positive for BRCA1/2 mutation (change or defect in the BRCA gene) or homologous recombination deficiency (when the body cannot repair breaks in DNA). The ...

Leukemia, other

Venetoclax Plus Chemotherapy For Newly Diagnosed Acute Myeloid Leukemia

This study focuses on people who have a new diagnosis of acute myeloid leukemia (AML) who agreed to participate in the MyeloMATCH study and were matched to this treatment trial. The purpose of the study ...

Lymphoid Leukemia

Poseida Therapeutics, Inc.,P-CD19CD20-ALLO1,PhI,Open-label,B-cell malignancies,P-CD19CD20-ALLO1

Primary Objective: To assess the safety and MTD or RDE of P-CD19CD20-ALLO1 based on dose limiting toxicities (DLT). Secondary Objectives: The safety of P-CD19CD20-ALLO1 The anti-B cell malignancy effect of P-CD19CD20-ALLO1 The effect of cell dose ...