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Treatment of Adult and Pediatric FSGS Using the LIPOSORBER LA-15 System

This study focuses on adults and children who have primary focal segmental glomerulosclerosis (FSGS- a disease of the kidney that causes large losses of protein in the urine) and whose kidney problems have remained despite ...


Amyotrophic lateral sclerosis (ALS), Neural Progenitor Cells, Stem Cells

CNS10-NPC-GDNF Delivered to the Motor Cortex for the Treatment of ALS

This study focuses on individuals who have been diagnosed with amyotrophic lateral sclerosis (ALS), with symptoms present for less than 3 years.  The purpose of the study is to examine the safety and effectiveness of ...


Heart Transplant, Heart failure

Heart Transplant, Heart Failure: Evaluating the Safety of Utilizing Donor Hearts from Donation after Circulatory Death (DCD) Donors compared to Donor Hearts from Donation after Brain Death (DBD) Donors (DCD IIT)

The purpose of this study is to evaluate the safety of using hearts from donors after circulatory death (DCD) compared to hearts from donors after brain death (DBD) in individuals who have been listed to ...


Heart transplant candidates

Development of Non-Invasive Cell-Free DNA to Supplant Invasive Biopsy in Heart Transplantation

This study focuses on adults who are undergoing heart transplant evaluation or are on the waiting list and expected to receive a heart transplant. The purpose of the study is to determine whether an investigational ...


APOL1-mediated Proteinuric Kidney Disease, Chronic kidney disease (CKD)

VX-147 in APOL1-Mediated Proteinuric Kidney Disease

The purpose of this study is to evaluate the safety and effects of an investigational drug called VX-147 in people who have APOL1-mediated chronic kidney disease (CKD), which occurs more frequently in people of African ...