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21 results found


APOL1-mediated Proteinuric Kidney Disease, Chronic kidney disease (CKD)

VX-147 in APOL1-Mediated Proteinuric Kidney Disease

The purpose of this study is to evaluate the safety and effects of an investigational drug called VX-147 in people who have APOL1-mediated chronic kidney disease (CKD), which occurs more frequently in people of African ...


Other

AntiBKV as Treatment: BKV Infection in Kidney Transplant Recipients

This study will evaluate an investigational drug called AntiBKV as a possible treatment for BK viremia (detection of BK virus in the blood) in kidney transplant recipients who have been diagnosed with BK viremia. Kidney ...


Other

Biomarker-Guided CNI Substitution in Kidney Transplantation

The purpose of this study is to evaluate whether a blood test can predict how a person’s immune system will respond to a transplanted kidney. Researchers also aim to determine whether a non-standard (experimental) drug ...


Other

BIVV020 for Prevention and Treatment of Antibody-Mediated Rejection in Adult Kidney Transplant Recipients

The purpose of the study is to evaluate whether an experimental medicine called BIVV020 can prevent antibody-mediated rejection (AMR) in patients with kidney transplants. BIVV020 is a type of antibody that binds to complement proteins. ...


Hodgkin's Lymphoma, Leukemia, not otherwise specified, Leukemia, other, Lymphoid Leukemia ...

Collecting and Combining Autologous Hematopoietic Stem Cells With (CAR) T-Cell Therapy in Hematological Malignancies

The purpose of this study is to assess the impact of adding blood stem cells to CAR T-cell therapy in an effort to improve cancer treatment. CAR T-cell therapy is a type of treatment in ...