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Functional Characterization of Post-Heart Transplant De Novo Donor Specific Antibodies

The purpose of this study is to identify unique characteristics of pathological donor-specific antibodies (DSAs). Pathological DSAs cause injury to the transplanted heart (also known as graft injury), unlike DSAs that may have attained immunological ...


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Hearts Transplanted After Non-Ischemic Heart Preservation from Extended Donors

The purpose of this study is to evaluate whether non-ischemic heart preservation (NIHP) of extended criteria donor hearts using the XVIVO Heart Preservation System (XHPS) is a safe and effective way to preserve and transport ...


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Tafamidis in Patients With Transthyretin-Mediated Amyloidosis Post Orthotopic Heart Transplantation

The purpose of this study is to determine whether tafamidis, an oral medication used to delay disease progression in adults with certain forms of transthyretin amyloidosis (ATTR), is effective in treating patients with heart transplants ...


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Recurrence Post-Transplant Observational Study in FSGS and MCD

This study focuses on adults and children who have been diagnosed with focal segmental glomerulosclerosis (FSGS) or minimal change disease (MCD) and who have had or are scheduled to have a kidney transplant. The purpose ...


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Advancing Transplantation Outcomes in Children

This study focuses on pediatric patients who are receiving a kidney transplant at Cedars-Sinai. The purpose of the study is to determine whether an experimental combination of immunosuppressive drugs, belatacept and sirolimus, preserves kidney ...