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7 results found


Nonalcoholic Fatty Liver Disease (NAFLD)

Role of Lisinopril in Preventing the Progression of Nonalcoholic Fatty Liver Disease

This study focuses on individuals who have a higher-than-average risk of developing liver cancer (hepatocellular carcinoma) due to their diagnosis of non-alcoholic fatty liver disease (NAFLD). NAFLD is a condition in which fatty cells accumulate ...


Gastrointestinal Cancer, Liver Cancer

Exact Science, ALTUS2021-01, at Risk for Hepatocellular Ca (HCC), Multi-Target Test Oncoguard

Primary Objective: Assess overall sensitivity and specificity of Oncoguard Liver for hepatocellular cancer (HCC) detection in a surveillance population. Secondary Objective(s): Assess performance of Oncoguard Liver in confirmed HCC and non-HCC population. Assess early-stage sensitivity of Oncoguard Liver ...


Other

Abbreviated MRI for HCC Screening in Cirrhotic Patients

The purpose of this study is to compare the diagnostic value of an abbreviated magnetic resonance imaging (MRI) protocol compared to ultrasound (or sonography) for screening of liver cancer. MRI uses magnetic waves to look ...


Other

Phase II Study of Unresectable Hepatocellular Carcinoma and Cirrhosis

The purpose of this study is to evaluate the effects of combined immunotherapy regimens (atezolizumab with bevacizumab) in patients with inoperable liver cancer and liver disease (cirrhosis). Participants may receive atezolizumab alone (if they are ...


Other

Efruxifermin in Compensated Cirrhosis Due to NASH/MASH

The purpose of this study is to evaluate the safety and effectiveness of an experimental drug called efruxifermin (EFX) for the treatment of compensated liver cirrhosis due to nonalcoholic steatohepatitis (NASH)/metabolic dysfunction-associated steatohepatitis (MASH). NASH/MASH ...