Find Clinical Trials | Cedars-Sinai

31 results found

Melanoma

OBX-115 in Unresectable or Metastatic Melanoma

The goal of this study is to determine the recommended dose of an experimental cell therapy called OBX-115 with another medication called acetazolamide (approved by the U.S. Food and Drug Administration as a mild diuretic) ...

Melanoma

Vusolimogene Oderparepvec in Combination With Nivolumab in Advanced Melanoma

The purpose of this study is to evaluate an experimental drug called vusolimogene oderparepvec (VO) in combination with another drug, nivolumab, in people who have advanced melanoma. Researchers will compare the effects of nivolumab with ...

Colon, Lip, Oral Cavity and Pharynx, Melanoma, Pancreas

IPN01194 as Single Agent in Advanced Solid Tumors

The purpose of this study is to evaluate an experimental drug called IPN01194 in people with selected mutations in advanced solid cancers. IPN01194 is a small molecule targeting a pathway called MAPK, which is frequently ...

Anus, Bones and Joints, Brain and Nervous System, Breast, Cervix ...

Molecular Analysis for Combination Therapy Choice (ComboMATCH)

The purpose of this study is to identify patients based on gene changes or mutations in their tumor for treatment using a combination of targeted therapy. The study focuses on patients who have had a ...

Brain and Nervous System, Breast, Colon, Lung, Other Endocrine System ...

mRNA-415 in Solid Tumors

The purpose of the trial is to evaluate the safety and effects of an experimental personalized vaccine called mRNA-4157, as well as to identify the best dose for future studies, in patients who have had ...