Find Clinical Trials | Cedars-Sinai

31 results found

Esophagus, Larynx, Lip, Oral Cavity and Pharynx, Lung, Melanoma

Safety and Effects of PF-08046031 in Advanced Melanoma and Other Solid Tumors

This clinical trial is for adults with advanced melanoma or certain other types of solid tumors. The goal is to learn more about a new investigational drug called PF-08046031, including how safe it is, how ...

Colon, Lung, Melanoma, Other Female Genital, Thyroid, Unknown Sites

KIN-2787 in Participants With BRAF and/or NRAS Mutation-Positive Solid Tumors

This early-phase clinical trial is designed for adults with advanced solid tumors that have spread (metastasized) and carry specific genetic mutations in the BRAF and/or NRAS genes—both of which are known to drive cancer progression. ...

Melanoma

PF-07799544 as a Single Agent and in Combination With Other Targeted Agents in BRAF-Mutant Melanoma and Other Solid Tumors

This study focuses on people who have melanoma (skin cancer) or other cancer with a specific change in the BRAF gene (BRAF alteration) and whose cancer has grown or spread. The study will explore the ...

Melanoma

Regeneron, R3767-ONC-2466, Ph2, open label, Melanoma, Fianlimab Plus Cemiplimab

Primary -Assess Overall Survival (OS) of patients with melanoma treated with Fianlimab Plus Cemiplimab in Expansion Cohorts from R3767-ONC-1613 Secondary -Assess Progression-Free Survival (PFS) -Assess Objective Response Rate (ORR) -Assess Duration of Response (DOR) -Assess Disease Control Rate (DCR) ...

Melanoma, Unknown Sites

SWOG, S2101, PhII, open label, Cabozantinib + Nivolumab, Melanoma or HNSCC

Primary Objective: 1. To evaluate the feasibility of molecular characterization based on tumor mutation burden (TMB) for participant stratification, as assessed by the proportion of participants with less than or equal to a 21-day ...