Inhaled Nitric Oxide for ARDS-Related Pulmonary Hypertension

What is the Purpose of this Study?

The purpose of this study is to determine whether giving inhaled nitric oxide to adults with acute respiratory distress syndrome (ARDS) who have developed pulmonary hypertension (elevated blood pressure in the blood vessels of the lungs) increases the likelihood that their condition will improve. Currently, there is no specific treatment for pulmonary hypertension that results from ARDS. Researchers want to learn whether the use of inhaled nitric oxide can improve pulmonary hypertension and thus improve the ability of other organs to work better. Participants will undergo an echocardiogram before taking inhaled nitric oxide and on days 2 and 4 of the study. Medical information, including vital signs and medications, will also be recorded. The use of inhaled nitric oxide to specifically target pulmonary hypertension in ARDS, as in this study, is investigational, although nitric oxide is frequently used for ARDS.


Eligibility

  • * Diagnosis of ARDS based on the Berlin criteria
  • * Mechanically ventilated
  • * Age ≥ 18 years
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Where can I participate?

Beverly

More about this Clinical Trial

What is the full name of this clinical trial?

A pilot study of inhaled nitric oxide for ARDS-related pulmonary hypertension and RV dysfunction.

Study Details
Disease Type/Condition

Other

Principal Investigator

Matusov, Yuri

Age Group

Adult

Phase

N/A

IRB Number

STUDY00001807

ClinicalTrials.gov ID

NCT06249633

Key Eligibility
ClinicalTrials.gov

How do I learn more about this study?
Email
clinicaltrials@cshs.org
Study Detail
Disease Type/Condition

Other

Principal Investigator

Matusov, Yuri

Age Group

Adult

Phase

N/A

IRB Number

00000486

ClinicalTrials.gov ID

NCT06249633

Key Eligibility
ClinicalTrials.gov

Contact
Email
clinicaltrials@cshs.org