What is the Purpose of this Study?
The purpose of this study is to evaluate the investigational use of a drug called bempedoic acid in individuals who have heterozygous familial hypercholesterolemia (HeFH). HeFH is a condition in which there are higher-than-normal amounts of low-density lipoprotein cholesterol (LDL-C) in the blood that is not sufficiently under control with current cholesterol-lowering medication(s). Researchers aim to determine how well bempedoic acid works to lower high LDL-C, how much of the drug is in participants’ blood, and how well it is tolerated in children and adolescents with high cholesterol.
Eligibility
- Written informed consent and assent (where applicable) Aged 6-17 years old Diagnosis of HeFH (heterozygous familial hypercholesterolemia) Treatment with approved stable lipid modifying therapies Fasting LDL-C greater than or equal to 130 mg/dL (3.4 mmol/L)
Where can I participate?
Beverly
More about this Clinical Trial
What is the full name of this clinical trial?
An Open-Label Study to Evaluate the Pharmacokinetics, Pharmacodynamics, and Safety of Bempedoic Acid in Pediatric Patients with Heterozygous Familial Hypercholesterolemia