Determinants of Incident Stroke Cognitive Outcomes and Vascular Effects on Recovery

What is the Purpose of this Study?

This study focuses on individuals who have had a recent (within 6 weeks) stroke and have no known history of dementia. The purpose of the study is to learn more about the factors that make people more or less likely to develop dementia (decline in memory, thinking, and other mental abilities that significantly affects daily functioning) after having a stroke. The study aims to identify patients at risk for dementia after their stroke so that future treatments may be developed to improve outcomes in stroke patients. For this study, a stroke is defined as an ischemic stroke (blood clot in the brain), intracerebral hemorrhage (bleeding in the brain), or an aneurysmal subarachnoid hemorrhage (bleeding around the brain caused by an abnormal bulge in a blood vessel that bursts). Researchers will review participants’ medical records and collect blood samples, as well as conduct interviews, physical and neurological exams, and cognitive assessments.


Eligibility

  • 1. Age ≥18 years
  • 2. Admitted to the hospital with a diagnosis of acute ischemic stroke (AIS), intracerebral hemorrhage (ICH), or aneurysmal subarachnoid hemorrhage (aSAH)
  • 3. Radiographic confirmatory evidence of: (1) AIS (based on a focal area of restricted diffusion on MRI), (2) non-traumatic ICH (based on evidence of acute parenchymal hemorrhage CT or brain MRI) or (3) non-traumatic acute aSAH (based on evidence of subarachnoid hemorrhage on CT or MRI and evidence of aneurysm on CT angiography, MR angiography, or conventional catheter-based angiography)
  • 4. Able to complete baseline visit in person or by phone within 6 weeks of stroke onset
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Where can I participate?

Beverly

More about this Clinical Trial

What is the full name of this clinical trial?

DETERMINANTS OF INCIDENT STROKE COGNITIVE OUTCOMES AND VASCULAR EFFECTS ON RECOVERY

Study Details
Disease Type/Condition

Other

Principal Investigator

Song, Shlee

Co-Investigators

Konrad Schlick

Age Group

Adult

Phase

N/A

IRB Number

STUDY00001088

ClinicalTrials.gov ID

NCT04916210

Key Eligibility
ClinicalTrials.gov

How do I learn more about this study?
Email
clinicaltrials@cshs.org
Study Detail
Disease Type/Condition

Other

Principal Investigator

Song, Shlee

Age Group

Adult

Phase

N/A

IRB Number

DISCOVERY

ClinicalTrials.gov ID

NCT04916210

Key Eligibility
ClinicalTrials.gov

Contact
Email
clinicaltrials@cshs.org