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Summary

This study focuses on patients who have chronic pancreatitis, pancreatic cancer, or no known pancreas disease. It is now recognized that a small portion of the population with diabetes have an underlying problem with their pancreas, such as chronic pancreatitis (when the pancreas is swollen and irritated all the time and affected by scarring) or pancreatic cancer, as the cause of their diabetes. Currently, there is no test to identify the small number of patients who have diabetes caused by a primary problem with their pancreas. The purpose of this study is to develop a blood test to distinguish various causes of diabetes. To this end, researchers will enroll a range of patients; most have developed diabetes within the last 3 years, but the study will also enroll a small number of patients with long-term diabetes and normal blood sugars for comparison. Participants will be asked to complete a questionnaire regarding their personal and family history, and a series of blood samples will be collected prior to and for 2 hours following consumption of a liquid nutritional supplement called Boost.


Inclusion Criteria

  • All patients must sign an informed consent indicating that they are aware of the investigational nature of this study. Patients must have signed an authorization for the release of their protected health information.
  • Patients must be ages ≥40 and <85.
  • Patients must have a diagnosis of one of the following based on study definitions;
  • New Onset Diabetes (<3 years) in subjects with Pancreatic Cancer (PDAC);
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Study Location(s)

Cedars-Sinai Cancer at SOCC

More about this Clinical Trial

Full Title

CPDPC16-04: Evaluation of a mixed meal test for Diagnosis and characterization of Type 3c diabetes mellitus secondary to pancreatic cancer and chronic pancreatitis

Details
Disease Type/Condition

Pancreas

Principal Investigator

Goodarzi, Mark

Co-Investigators

Andrew Hendifar, Artak Labadzhyan, Christie Jeon, Jun Gong, Nicholas Nissen, Quin Liu, Ruchi Mathur, Simon Lo, Srinivas Gaddam, Stephen Pandol, Wendy Sacks

Age Group

Adult

Phase

N/A

IRB Number

Pro00050528

ClinicalTrials.gov ID

NCT03460769

Key Eligibility
ClinicalTrials.gov

Contact
Email
cancer.trial.info@cshs.org
Want to join the study or
learn more?

Details
Disease Type/Condition

Pancreas

Principal Investigator

Goodarzi, Mark

Age Group

Adult

Phase

N/A

IRB Number

EIIT-CPDPC16-04

ClinicalTrials.gov ID

NCT03460769

Key Eligibility
ClinicalTrials.gov

Contact
Email
cancer.trial.info@cshs.org
Want to join the study or
learn more?