ICECAP

Summary

Brain injury causing coma after cardiac arrest can be fatal or may prevent patients from recovering. This study focuses on comatose, adult survivors of out-of-hospital cardiac arrest that have already been rapidly cooled per standard of care. Therapeutic hypothermia (cooling the body and brain a few degrees below normal temperature) is a standard treatment in which comatose patients are rapidly cooled to improve their chances of recovery. The purpose of the study is to determine whether different lengths of time for body cooling affect recovery; researchers want to learn more about a way to possibly lessen brain injury after cardiac arrest. Standard practice is to cool patients for about a day, but the best length of time is not known. After treatment, researchers will contact participants or their caregivers about once per month to see how the participant is doing.


Inclusion Criteria

  • Coma after resuscitation from out of hospital cardiac arrest
  • Cooled to <34 deg C with 240 minutes of cardiac arrest
  • Definitive temperature control applied
  • Age ≥ 18 years
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Study Location(s)

Beverly

More about this Clinical Trial

Full Title

ICECAP: Influence of Cooling duration on Efficacy in Cardiac Arrest Patients

Details
Disease Type/Condition

Brain Injury

Principal Investigator

Toossi, Shahed

Co-Investigators

Maranatha Ayodele, Michael Gezalian, Sam Torbati, Shouri Lahiri

Age Group

Adult

Phase

N/A

IRB Number

STUDY00000673

ClinicalTrials.gov ID

NCT04217551

Key Eligibility
ClinicalTrials.gov

Contact
Email
clinicaltrials@cshs.org
Want to join the study or
learn more?

Details
Disease Type/Condition

Brain Injury

Principal Investigator

Toossi, Shahed

Age Group

Adult

Phase

N/A

IRB Number

ICECAP

ClinicalTrials.gov ID

NCT04217551

Key Eligibility
ClinicalTrials.gov

Contact
Email
clinicaltrials@cshs.org
Want to join the study or
learn more?