Mechanisms of Glutamine Metabolism in Prostate Cancer Progression

What is the Purpose of this Study?

This study focuses on patients with a specific stage of prostate cancer known as metastatic, castration-sensitive or metastatic, castration-resistant prostate cancer who are still receiving androgen targeting therapy (a type of prostate cancer therapy). The purpose of the study is to examine the role of glutamine (amino acid or component of protein found in our bodies and a variety of foods), 4E-BP1 (molecule involved in glutamine metabolism), and T-cell (immune cell) levels in the blood of these patients with prostate cancer. Researchers want to know whether the levels help predict benefit from prostate cancer therapies and the likely course of prostate cancer. Study procedures include blood collections and medical history review.


Eligibility

Not Available


Where can I participate?

  • CS Cancer at Beverly Hills
  • CS Cancer at Cedars-Sinai Medical Center



What is the full name of this clinical trial?

IIT2019-09-GONG-MCRPC: Mechanisms of Glutamine Metabolism in Prostate Cancer Progression and Resistance to Androgen Signaling Blockade

Study Details
Disease Type/Condition

Prostate

Principal Investigator

Gong, Jun

Co-Investigators

Edwin Posadas, Howard Sandler, Hyung Kim, Kevin Scher, Leland Chung, Mitchell Kamrava, Mourad Tighiouart, Stephen Freedland, Timothy Daskivich, Zachary Zumsteg

Age Group

Adult

Phase

N/A (Cancer Control)

IRB Number

STUDY00000070


How do I learn more about this study?
Email
clinicaltrials@cshs.org
Study Detail
Disease Type/Condition

Prostate

Principal Investigator

Gong, Jun

Age Group

Adult

Phase

N/A (Cancer Control)

IRB Number

IIT2019-09-GONG-MCRPC


Contact
Email
clinicaltrials@cshs.org