This study focuses on individuals who have Gaucher disease, a condition in which fatty substances accumulate in certain organs. The purpose of the study is to identify factors in the blood of Gaucher patients that could lead to the development of monoclonal gammopathy (MG) or multiple myeloma (MM). MG and MM are more common in Gaucher patients, for unknown reasons. MG is a non-cancerous condition in which the body makes an abnormal protein (paraprotein). MM is a cancer that forms in a type of white blood cell called a plasma cell. This study will collect blood samples to examine the function of B cells, Gaucher biomarkers, and specific genes involved in B cell function. B cells are a type of white blood cell that play an important part in the body’s immune system. Researchers hope that by analyzing B cells, they can identify clues to the development of MG or MM in Gaucher patients.

• Cedars-Sinai Cancer at Beverly Hills (THO) : Saba Mukarram
• Cedars-Sinai Cancer at SOCC : Saba Mukarram