What is the Purpose of this Study?
The purpose of this study is to evaluate whether meal timing (changing when you eat) is beneficial during active cancer treatment in reducing side effects from chemotherapy and radiation in people who have been diagnosed with rectal or breast cancer (HER2+ or triple negative). The study aims to determine whether altering an individual’s eating schedule can help shrink tumors and improve health and wellbeing. Participants will be randomly assigned to 1 of 2 groups. One group will eat within an 8-hour or shorter period daily, starting 1-3 hours after waking up. The other group will eat over a 12-hour or longer period daily. Participants will be asked to follow their eating schedule 6 days per week. Study procedures also include blood draws, questionnaires, and activity monitoring.
Eligibility
- * Any sex/gender of any ethnic/racial background
- * Age greater than or equal to 18 years
- * Histologically-confirmed rectal cancer stage II, III, or IV (if curative) or human epidermal growth factor receptor 2-positive (HER2+) or triple negative breast cancer stage I, II, or III (only if definitive intent) per American Joint Committee on Cancer (AJCC) criteria
- * BMI 18.5 kg/m2 or greater
Where can I participate?
- CS Cancer at Beverly Hills : Nathalie Nguyen
- CS Cancer at Cedars-Sinai Medical Center : Nathalie Nguyen
- Hunt Cancer Institute, an Affiliate of Cedars-Sinai Cancer
- University of Alabama (Study Affiliate)
More about this Clinical Trial
What is the full name of this clinical trial?
IIT2020-26-FIGUEIREDO-TRE: Time-Restricted Eating and Cancer: Clinical Outcomes, Mechanisms, and Moderators