Intensive Cholesterol-Lowering and CD8+ T Cells in Prostate Cancer

What is the Purpose of this Study?

The purpose of this study is to determine whether a commonly used cholesterol-lowering therapies can help recruit antitumor immune cells into a prostate tumor. The study focuses on people with prostate cancer who have elected to monitor their cancer under active surveillance and who will have a standard-of-care biopsy in 3-6 months. Study procedures include receiving medication (usually Vytorin but can differ depending on cholesterol level and any current anti-cholesterol therapy), undergoing blood tests, and completing questionnaires. All study medications are approved by the U.S. Food and Drug Administration (FDA) for cholesterol-lowering, but their use in this study is considered experimental because it has not been approved to stop the growth of prostate cells in individuals with prostate cancer.


Eligibility

Not Available


Where can I participate?

Beverly


What is the full name of this clinical trial?

IIT2024-01-KIM-ICL: Intensive Cholesterol-Lowering and CD8+ T Cells in Prostate Cancer

Study Details
Disease Type/Condition

Prostate

Principal Investigator

Kim, Hyung

Co-Investigators

Andriana Nikolova, Michael Ahdoot, Patricia Thompson-Carino, Stephen Freedland, Timothy Daskivich

Age Group

Adult

Phase

II

IRB Number

STUDY00003290


How do I learn more about this study?
Email
clinicaltrials@cshs.org
Study Detail
Disease Type/Condition

Prostate

Principal Investigator

Kim, Hyung

Age Group

Adult

Phase

II

IRB Number

IIT2024-01-KIM-ICL


Contact
Email
clinicaltrials@cshs.org