Molecular Transducers of Physical Activity Consortium

What is the Purpose of this Study?

The purpose of this study is to understand how exercise affects the cells and tissues in the body to bring about health benefits. Highly active and sedentary participants will be enrolled. The study will conduct baseline tests of body composition, exercise endurance, and muscle strength. Samples of blood and small pieces of muscle (from the thigh) and fat tissue (from the waist region) will also be obtained to examine the function of different molecules and how they change with exercise. Sedentary participants will then be randomly assigned to 1 of 3 groups: 1) endurance exercise training (treadmill and stationary bike) 2) resistance exercise training (weight lifting), or 3) no exercise training. Participants assigned to endurance or resistance exercise training will undergo supervised exercise sessions 3 times per week for approximately 3 months, after which all baseline assessments will be repeated.


Eligibility

  • * Willingness to provide informed consent to participate in the MoTrPAC Study
  • * Must be able to read and speak English well enough to provide informed consent and understand instructions
  • * Aged ≥18 y
  • * Body Mass Index (BMI) ≥19 to ≤35 kg/m2
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Where can I participate?

Beverly

More about this Clinical Trial

What is the full name of this clinical trial?

Molecular Transducers of Physical Activity

Study Details
Disease Type/Condition

Geriatrics, Molecular responses to exercise

Principal Investigator

Musi, Nicolas

Age Group

Adult

Phase

II

IRB Number

STUDY00002499

ClinicalTrials.gov ID

NCT03960827

Key Eligibility
ClinicalTrials.gov

How do I learn more about this study?
Email
clinicaltrials@cshs.org
Study Detail
Disease Type/Condition

Geriatrics, Molecular responses to exercise

Principal Investigator

Musi, Nicolas

Age Group

Adult

Phase

II

IRB Number

MOTRPAC

ClinicalTrials.gov ID

NCT03960827

Key Eligibility
ClinicalTrials.gov

Contact
Email
clinicaltrials@cshs.org