The specific proposed objectives of this study are the following: 1. To characterize the clinical population of patients with SIH attending quaternary (Cedars-Sinai Medical Center) and tertiary (Headache Clinic, University of Calgary, and CSF Leak clinic, University of Toronto) clinics. This would include characterizing clinical features, diagnostic imaging results, and interventions completed before first clinic visit. 2. To determine efficacy of various interventions (percutaneous procedures, endovascular embolization, and spine surgery) by assessing data on various outcomes at baseline and at various time intervals after intervention (24 hours, 4 weeks, 3 months, 6 months, 12 months, and then yearly up to 5 years following intervention). 3. For patients who do not pursue intervention, the same outcomes will be assessed at baseline and then starting at 3 months following baseline visit. 4. To determine adverse effects and complications related to each intervention and the timeline of occurrence. 5. To assess the correlation or association of leak type with intervention type and its efficacy. For e.g. prospectively assessing the efficacy of percutaneous procedures in patients with Type 1 to 4 leaks. 6. To compare interventions for each specific leak type. For e.g. endovascular embolization vs. spinal surgery for patients with CSF-venous fistulas.
Not Available
What is the full name of this clinical trial?
Prospective Observational Study of Patient Outcomes after various interventions for Spontaneous Intracranial Hypotension