This study aims to determine whether 2 surgical procedures are no different for ovarian cancer risk reduction in individuals with BRCA1 mutations who have completed childbearing. Researchers will compare the removal of fallopian tubes to the removal of fallopian tubes and ovaries. The study will also examine the factors that go into deciding which surgery to have, as well as evaluate the symptoms after surgery (symptoms caused by lack of estrogen due to ovary removal). The usual treatment approach is surgery to remove the fallopian tubes and ovaries at the same time. Participants will decide whether to undergo surgical removal of fallopian tubes (bilateral salpingectomy) or removal of fallopian tubes and ovaries (bilateral salpingo-oophorectomy).
What is the full name of this clinical trial?
A Non-Randomized Prospective Clinical Trial Comparing the Non-Inferirority of Salpingectomy to Salpingo-Oophorectomy to Reduce the Risk of Ovarian Cancer Among BRCA1 Carriers [SOROCk]
Rimel, Bobbie Jo
Andrew Li, Kenneth Kim, Kristin Taylor, Margaret Liang