UVA Light Device to Treat COVID-19

What is the Purpose of this Study?

To demonstrate basic safety and proof of principle for Endotracheal UV Light Device. Primary Endpoint: Reduction of viral load in upper airway in patients admitted to hospital positive for COVID-19. Secondary Endpoints: Overall reduction or change for the following endpoints: - Bacterial load in upper airway - Development of ventilated associated pneumonia (VAP) - Days to extubation - Days to Discharge - Inflammatory marker changes (IL-6, CRP) - O2 requirement - Western blot for Spike protein in upper airway - 7-point Clinical Outcomes: death, hospitalized on ventilator or ECMO, hospitalized on non-invasive ventilation, hospitalized on supplemental O2, hospitalized not on O2, not hospitalized but with limitations, not hospitalized and no limitations. - Culture of endotracheal tube tip from extubated patients


Eligibility

Not Available


Where can I participate?

Beverly


What is the full name of this clinical trial?

Respiratory application of a novel ultraviolet light delivery device for patients infected with COVID-19: A Pilot Study

Study Details
Disease Type/Condition

Other

Principal Investigator

Chaux, George

Co-Investigators

Ali Rezaie, Gil Melmed, Isabel Pedraza, Mark Pimentel, Michael Lewis, Ruchi Mathur, Will Takakura

Age Group

Adult

Phase

I

IRB Number

STUDY00000883


How do I learn more about this study?
Email
clinicaltrials@cshs.org
Study Detail
Disease Type/Condition

Other

Principal Investigator

Chaux, George

Age Group

Adult

Phase

I

IRB Number

STUDY00000883


Contact
Email
clinicaltrials@cshs.org