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PRIOH-1 Phase 3 (Part C, D, and E)

Primary Objectives: - Part C: To investigate the efficacy of oral pritelivir 100 mg once a day in immunocompromised subjects with ACV-R mucocutaneous HSV infections for a treatment period of 28 days as a maximum in ...


Brain and Nervous System

Identification of Pre-Malignant Lesions In Pediatric Patients With Neurofibromatosis Type 1

The purpose of this study is to evaluate the use of a magnetic resonance imaging (MRI) technique called whole-body MRI, combined with a computer program, in children and adolescents (5-18 years old) with neurofibromatosis type ...


Other

Sparsentan Treatment in Pediatric Subjects

The purpose of this study is to determine the safety and effectiveness of an investigational drug called sparsentan in the treatment of kidney diseases and whether it is safe to use in children who are ...


Congenital heart

Edwards SAPIEN 3 Transcatheter Pulmonary Valve System with Alterra Adaptive Prestent

The purpose of this study is to evaluate the safety and effectiveness of the Edwards SAPIEN 3 Transcatheter Pulmonary Valve System with the Alterra Adaptive Prestent, which is approved by the U.S. Food and Drug ...


Hand ligament reconstruction surgery

Hand Ligament Reconstructions With Knee Collateral Ligament Allografts

The purpose of this study is to review clinical outcomes following hand ligament reconstruction surgery using allograft (cadaveric) knee collateral ligaments. Researchers believe that the use of allograft ligaments may eliminate the pain associated with ...