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PRIOH-1 Phase 3 (Part C, D, and E)

Primary Objectives: - Part C: To investigate the efficacy of oral pritelivir 100 mg once a day in immunocompromised subjects with ACV-R mucocutaneous HSV infections for a treatment period of 28 days as a maximum in ...


Brain and Nervous System

Identification of Pre-Malignant Lesions In Pediatric Patients With Neurofibromatosis Type 1

The purpose of this study is to evaluate the use of a magnetic resonance imaging (MRI) technique called whole-body MRI, combined with a computer program, in children and adolescents (5-18 years old) with neurofibromatosis type ...


Other

Sparsentan Treatment in Pediatric Subjects

The purpose of this study is to determine the safety and effectiveness of an investigational drug called sparsentan in the treatment of kidney diseases and whether it is safe to use in children who are ...


Congenital heart

Edwards SAPIEN 3 Transcatheter Pulmonary Valve System with Alterra Adaptive Prestent

The purpose of this study is to evaluate the safety and effectiveness of the Edwards SAPIEN 3 Transcatheter Pulmonary Valve System with the Alterra Adaptive Prestent, which is approved by the U.S. Food and Drug ...


Brain and Nervous System

Carboplatin and Vincristine Versus Selumetinib in Low-Grade Glioma

This study focuses on individuals who have been diagnosed with a cancer called low-grade glioma (LGG). The purpose of the study is to determine whether an experimental drug called selumetinib is as effective as the ...