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OHB-607 Compared to Standard Neonatal Care for the Prevention of Bronchopulmonary Dysplasia

Babies born prematurely often have problems with their lungs and breathing. The purpose of this study is to determine whether an experimental drug called mecasermin rinfabate (OHB-607) can decrease the risk of breathing problems and ...


Kidney

Risk-Adapted Treatment of Unilateral Favorable Histology Wilms Tumors

The purpose of this study is to improve outcomes for children with a diagnosis of favorable histology Wilms tumor (FHWT), a cancer type in which certain microscopic characteristics of tumor cells are associated with a ...


Other

BD BACTECTM FXI Culture System vs BD BACTECTM FX in the Detection of Bloodstream Infections

The purpose of this study is to collect blood cultures from individuals suspected of having a blood stream infection (BSI). A BSI is caused by bacteria or fungi in the blood stream that causes one ...


Other

p19 Inhibition of the IL-23 Pathway to Establish Efficacy in Pediatric Crohn’s Disease

The purpose of this study is to determine whether the experimental drugs guselkumab and mirikizumab work in patients with moderate to severe Crohn’s disease (CD) who are 2 to 17 years old and have not ...


Other

Zorevunersen (STK-001) in Patients With Dravet Syndrome

The purpose of this study is to determine whether an experimental drug called zorevunersen (STK-001) works to reduce the number of seizures for children and adolescents with Dravet syndrome. Dravet syndrome is a severe form ...