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387 results found


Brain and Nervous System

Primary CNS Lymphoma: Phase I Trial of Methotrexate, Rituximab, Lenalidomide, and Nivolumab

The purpose of this study is to determine whether the drugs rituximab, methotrexate, lenalidomide, and nivolumab can be safely combined for treatment of primary CNS lymphoma. Researchers also want to learn which dose is the ...


COVID-19

Pituitary Function and Fatigue Symptoms in Patients Who Have Recovered from COVID-19

This study focuses on individuals who were previously diagnosed with COVID-19 infection. The study will examine how COVID-19 affects endocrine hormone function and whether changes in hormone levels impact symptoms such as fatigue, weakness, low ...


Prostate

Prostate Oligometastatic Radiotherapy With or Without Androgen Deprivation Therapy in Oligometastatic Prostate Cancer

This study focuses on individuals with prostate cancer. The purpose of the study is to evaluate whether a drug called relugolix plus the usual radiation therapy delays the spread of cancer compared to the usual ...


Obesity, Weight management

Allurion Gastric Balloon System for the Treatment of Adults with Obesity

The purpose of this study is to evaluate the safety and potential advantages of an investigational device called the Allurion Gastric Balloon System (AGBS), which has been developed for the treatment of adult individuals who ...


Other

Triscuspid Regurgitation: Edwards PASCAL TranScatheter Valve Repair System

The purpose of this study is to evaluate the safety and effectiveness of an experimental device called the PASCAL System with optimal medical therapy (OMT) compared to OMT alone in patients with symptomatic severe tricuspid ...