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Single Versus Multiple Arterial Grafts: The ROMA WOMEN Trial

The purpose of this study is to determine the effect of single versus multiple arterial revascularization (the restoration of blood flow to an organ) for female patients undergoing coronary artery bypass surgery. Currently, an artery ...


Multiple Sclerosis

Lesion-Specific Mechanisms Driving Degeneration of the Visual Axis in Multiple Sclerosis

The purpose of this study is to evaluate the effects of multiple sclerosis (MS) lesions in the visual pathway and how they contribute to nerve cell loss in the retina and impact visual function over ...


Other

Auxora in Acute Pancreatitis and Accompanying Systemic Inflammatory Response Syndrome

The purpose of this study is to determine whether an experimental drug called Auxora is safe to use in people who have acute pancreatitis with accompanying systemic inflammatory response syndrome (SIRS). Acute pancreatitis with SIRS ...


Brain and Nervous System

Chemotherapy Followed By WVSCI For Non-Germinomatous Central Nervous System Germ Cell Tumor

This study focuses on individuals who have been diagnosed with a type of brain cancer called non-germinomatous germ cell tumor (NGGCT) and whose tumor is “localized” (has not spread to other parts of the brain ...


Breast cancer

De-Escalation of Therapy in Early-Stage TNBC

This study focuses on patients who have been diagnosed with early-stage, triple-negative breast cancer (TNBC) and have recently completed preoperative chemotherapy in combination with the immunotherapy drug pembrolizumab, followed by breast surgery. The purpose of ...