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Outcomes of Children Newly Diagnosed with Crohn’s Disease

The purpose of this study is to determine the reasons why some children with newly diagnosed Crohn’s disease (CD) heal their bowel inflammation after one type of therapy and why others do not. CD is ...


Other

AZD3427 in Heart Failure and Pulmonary Hypertension Due to Left Heart Disease

The purpose of this study is to evaluate the effectiveness, safety, and tolerability of an experimental drug called AZD3427, given in addition to standard-of-care medication, in patients with heart failure and pulmonary hypertension due to ...


Other

Inhaled Nitric Oxide for ARDS-Related Pulmonary Hypertension

The purpose of this study is to determine whether giving inhaled nitric oxide to adults with acute respiratory distress syndrome (ARDS) who have developed pulmonary hypertension (elevated blood pressure in the blood vessels of the ...


Colon, Rectum

Metastatic Colorectal Cancer: Evaluating Radiation, Ablation, and Surgery

This study focuses on individuals who have advanced colorectal cancer that has spread up to 4 body sites. The purpose of the study is to compare the usual treatment alone to ablative local therapy (ALT) ...


Other

SELUTION SLR 014 Drug Eluting Balloon in the Treatment of In-Stent Restenosis

The purpose of this study is to demonstrate whether an investigational device called the SELUTION SLR drug eluting balloon is well tolerated and whether it works as effectively as other currently available treatments for patients ...