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387 results found


APOL1-mediated Proteinuric Kidney Disease, Chronic kidney disease (CKD)

VX-147 in APOL1-Mediated Proteinuric Kidney Disease

The purpose of this study is to evaluate the safety and effects of an investigational drug called VX-147 in people who have APOL1-mediated chronic kidney disease (CKD), which occurs more frequently in people of African ...


Movement Disorders, Parkinson's Disease

BIIB122 in Parkinson's Disease

This study will evaluate whether an investigational drug called BIIB122 is safe and effective in people with early-stage Parkinson’s disease (PD) who are 30-80 years old. The study also aims to learn how the body ...


Breast cancer, Colon cancer, Lung Cancer, Melanoma, Rectal Cancer, Solid ...

GV20-0251 in Advanced and/or Refractory Solid Tumor Malignancies

The purpose of the study is to determine whether an experimental drug called GV20-0251 is safe and tolerable in patients with solid tumors that have not been successfully treated with standard therapies. GV20-0251 is a ...


Transgender Medicine

Remote Activity Assessment and PRO Collection Among Transgender Cancer Survivors

This study will examine the role of wrist-worn activity monitors (Fitbit) in the care of transgender cancer patients and survivors. Researchers aim to determine whether participants’ daily activity (e.g., daily step counts, stairs climbed) and ...


Glioblastoma, Lifestyle

Glioblastoma: Ketogenic Diet Versus Standard Dietary Guidance

The purpose of this study is to examine the effects of an 18-week ketogenic diet (high fat, moderate protein, very low carbohydrate diet) on overall survival of glioblastoma (a type of brain cancer). Researchers also ...