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Intraoperative Monitoring: Lateral Lumbar Interbody Fusion Procedure

The purpose of this study is to document the usefulness of an intraoperative neuromonitoring (IONM) system that is already established and approved by the U.S. Food and Drug Administration (FDA). The system is used to ...


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Volumetric Echocardiographic Particle Image Velocimetry in Mitral Valve Regurgitation

The purpose of this study is to evaluate a technique to measure the severity of leakage of the mitral valve in people with mitral valve regurgitation. Mitral valve regurgitation is a condition which, if untreated ...


Bones and Joints, Breast, Cervix, Colon, Kidney, Liver, Lung, Melanoma ...

PARG Inhibitor IDE161 in Advanced Solid Tumors

This study focuses on individuals who have a solid tumor cancer (not a blood cancer) that has worsened and has not responded to at least one prior cancer treatment. The purpose of the study is ...


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Functional Characterization of Post-Heart Transplant De Novo Donor Specific Antibodies

The purpose of this study is to identify unique characteristics of pathological donor-specific antibodies (DSAs). Pathological DSAs cause injury to the transplanted heart (also known as graft injury), unlike DSAs that may have attained immunological ...


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Treprostinil Therapy to Reverse Right Ventricular Remodeling in Pulmonary Arterial Hypertension

The purpose of this study is to evaluate whether giving a drug called treprostinil earlier in a patient’s pulmonary arterial hypertension (PAH) diagnosis and then quickly increasing the dose will improve the patient’s PAH symptoms ...