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387 results found


Melanoma

IMC-F106C Plus Nivolumab Versus Nivolumab Regimens in Advanced Melanoma

This study focuses on adults with advanced melanoma (a type of skin cancer) that has spread or cannot be surgically removed. The purpose of the study is to determine whether an experimental drug called IMC-F106C, ...


Other

Cerebral Protection in Transcatheter Aortic Valve Replacement

The purpose of this study is to evaluate the safety and feasibility of an experimental filter system called the ProtEmbo Cerebral Protection System (ProtEmbo Device) in patients who are undergoing TAVR and have a risk ...


Movement Disorders

Syn-Sleep Study

The purpose of the study is to evaluate the use of an experimental test called the Syn-One Test for identifying patients with idiopathic rapid eye movement sleep disorder (iRBD) that will progress to synucleinopathies (a ...


Other

Balloon-Expandable Bioprosthetic SAPIEN X4 Transcatheter Heart Valve in Failing Aortic Bioprosthetic Valves

This study focuses on people who have an existing bioprosthetic aortic valve that is failing and needs to be replaced and who fall in the high or greater risk category for open heart surgery. The ...


Prostate

Intensive Cholesterol-Lowering and CD8+ T Cells in Prostate Cancer

The purpose of this study is to determine whether a commonly used cholesterol-lowering therapies can help recruit antitumor immune cells into a prostate tumor. The study focuses on people with prostate cancer who have elected ...